Controlled and Enhanced Drug Delivery Into and Through the Skin

Pre-Meeting Workshop

Date/Time: Saturday, July 20, 2019 - 8:00 AM to 5:00 PM
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Description:

The objective is to provide an overview of the state-of-the-art of controlled and enhanced drug delivery into - for the purpose of local therapy - and through the skin to achieve a systemic therapeutic effect.  Topics include modern topical formulation design, new therapies and tools in topical drug product development, assessment of local bioavailability and bioequivalence, skin pharmacokinetic modelling, biophysical techniques to monitor drug penetration across skin, current and future applications of passive and facilitated transdermal drug technology, and the potential for macromolecular delivery.  The workshop is targeted to pharmaceutical scientists and bioengineers, with interests in the skin-delivery system interface, from industry, academia and government.

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8:15 AM – 8:30 AM
Introduction
M.B. Delgado-Charro & R.H. Guy

8:30 AM – 9:15 AM
Modern Topical Formulation Design
Professor Adrian Davis, UCL and Limeway Pharma Design, UK

9:15 AM – 10:00 AM
New Therapies and Tools in Topical Drug Product Development
Professor Marc Brown, MedPharm, UK

10:00 AM – 10:30 AM
Coffee Break

11:00 AM – 11:45 AM
Assessment of Local (Skin) Bioavailability and Bioequivalence
Dr. Wing-Sin Chiu, Pfizer, UK

11:45 AM – 12:30 PM
Skin Pharmacokinetic Modelling
Professor Annette Bunge, Colorado School of Mines, US

12:30 PM – 1:00 PM
Round-Table Discussion
Speakers & Co-Chairs

1:00 PM – 2:00 PM
Lunch

2:00 PM – 2:45 PM
Biophysical Techniques to Monitor Drug Penetration Across Skin
Professor Richard Guy, University of Bath, UK

2:45 PM – 3:30 PM
Current and Future Applications of Passive Transdermal Drug Delivery
Dr. Takaaki Terahara, Himitsu, Japan

3:30 PM – 4:00 PM
Coffee Break

4:00 PM – 4:45 PM
Microneedle-Enabled Transdermal Drug Delivery
Professor Ryan Donnelly, Queen’s University, Belfast, UK

4:45 PM – 5:30 PM
Macromolecular Drug Delivery Across the Skin
Professor Samir Mitragotri, Harvard University, US

5:30 PM – 6:00 PM
Round-Table and Concluding Remarks
Speakers and co-chairs

Speaker(s):