Basic Concepts of Oral Drug Delivery; What You Need to Know

Pre-Meeting Workshop

Date/Time: Saturday, July 20, 2019 - 8:00 AM to 5:00 PM
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Members of the CRS often comment that the Society has helped them in many ways but first and foremost in exposing them to the collective knowledge of its members. Newcomers usually find the first meetings confusing, in particular, if they are used to “focused” meetings. As an example, a polymer scientist developing a product that might be useful in the CR context might have little or no knowledge about the physiological conditions his/her polymer might encounter after ingestion. Conversely, a clinician with a problem that might be solved with CR might know little or nothing about materials sciences or CR technologies. This workshop attempts to give an oversight covering the “usual (known to us) unknowns”


9:00 AM – 9:15 AM
Welcome and Introductions
Daniel Bar Shalom & Ali Rajabi-Siahboomi

9:15 AM – 10:00 AM
Understanding the GI Tract for Drug Delivery
Clive G Wilson, SIPBS, Glasgow, U.K.

10:00 AM – 10:40 AM
Developability of New Chemical Entities - Role of Excipients
Keith Horspool, Boehringer Ingelheim, USA

10:40 AM – 11:00 AM
Morning Break & Networking

11:00 AM – 11:40 AM
Basic Principles of Difference Drug Release Profiles 
Ali Rajabi-Siahboomi, Colorcon, USA

11:40 AM – 12:20 PM
Modifying Drug Delivery: Delayed Release
Daniel Bar Shalom, University of Copenhagen, Denmark

12:20 PM – 1:20 PM
Lunch Break

1:20 PM – 2:00 PM
Recent Advances in Achieving Solubility Enhancement
Meinolf Brackhagen, Dupont, Germany

2:00 PM – 2:40 PM
Solubility Enhancement Using Hot Melt Extrusion Technology
Christian Mühlenfeld, Ashland, USA

2:40 PM – 3:20 PM
Taste Masking, Keeping Young and Elderly in Mind
Manish Rane, Colorcon, USA

3:20 PM – 3:40 PM
Afternoon Break & Networking

3:40 PM – 4:20 PM
Predicting Bio-Performance and Bioequivalence of MR Formulations Using In-Vitro or In-Silico Methods
Sandra Klein, Universitaet Greifswald, Germany

4:20 PM – 5:00 PM
Lipid based drug delivery system
Anette Mullertz, University of Copenhagen, Denmark

5:00 PM
Questions & Roundtable Discussion
All Speakers